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1.
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The PBT Profiler is a predictive screening tool to be used when data are not
available.
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2.
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For technical reasons, there are certain chemicals
(or chemical classes) that should not be profiled with the PBT Profiler.
More information
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| 3.
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The PBT Profiler is a screening tool, PBT estimations rendered by the
PBT Profiler are not sufficient for definitive PBT determinations. The
PBT Profiler is a research, not regulatory, tool to identify chemicals
that may need further evaluation for potential Persistence,
Bioaccumulation and Toxicity characteristics.
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| 4.
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EPA does not use the PBT Profiler to assess and identify new chemicals submitted
as PreManufacture Notices (PMNs) under the Toxic Substances Control Act, as being
in the New Chemicals Category for Persistent, Bioaccumulative, and Toxic Chemicals.
Professional judgment of EPA OPPT subject matter experts is used to assign PBT concern
levels to PMNs. The PBT Profiler does contain the same computer models used by EPA to
screen PMNs for “P” and “B”. However, for PMNs, “T” is determined by EPA OPPT human
health experts using nearest analog analysis and is based on chronic oral
systemic toxicity to humans, mammals, and birds.
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To continue using the PBT Profiler, please acknowledge that you
have read and understand the issues and considerations discussed above:
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